This multi-national program applies a breakthrough approach to childhood obesity called, Brain-to-Society (BtS) Diagnostic Approach. In Montreal, Canada and Palwal, India, the investigators will recruit two cohorts of 612 children (6 to 12 years; 306 boy/306 girls) where Whole-of-Society (WoS) transformations are taking place (industrialized societal context with peaking childhood obesity and where a broad governmental plan to promote healthy lifestyle has been adopted -Canada; developing societal context with increasing childhood obesity if replication of past pathways that have lead to double burden; India) are taking place along with World Health Assembly (WHA) resolution A63-12 for marketing of food to children. Individual-level BtS Diagnostic will examine the degree to which individual differences in genetics and biology and differences in the environmental exposures modulate the behavioral, body weight/fatness and nutritional risk over time in the context of WoS transformations. Societal-level BtS Diagnostic shall examine the influence of decisions in policy, investment, business and innovation made by different stakeholders (government, private sector, civil society in health and non-health society systems including agriculture, business and media practices) on the community.
Study Type
OBSERVATIONAL
Enrollment
1,224
McGill Centre for the Convergence of Health and Economics (MCCHE)
Montreal, Quebec, Canada
The INCLEN Trust International
New Delhi, India
Individual-level BtS Diagnostic 1
Genotyping and detection of the Taq1A allele in the dopamine-2 receptor (DRD2) gene.
Time frame: 2 years
Individual-level BtS Diagnostic 2
Genotyping and detection of the exon 3 7-repeat allele of the dopamine-4 receptor (DRD4) gene.
Time frame: 2 years
Behavioral Assessment
Assess behavior of each participant in relation to food choice
Time frame: 2 years
Body Weight Assessment
Assess body weight of each participant
Time frame: 2 years
Nutritional Risk Assessment
Assess nutrition intake for each participant.
Time frame: 2 years
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