Single incision laparoscopic surgery (SILS) is the further development of the concept of minimally invasive surgery for colorectal cancer,which rapidly developed in the field of colorectal surgery. Through the development of single hole laparoscopic colorectal cancer radical surgery and clinical study and follow up accordingly, evaluating the feasibility, surgical effectiveness and economy help to promote the popularization and application of single hole laparoscopic techniques in the field.
The patients with colorectal cancer will randomly divided into single incision laparoscopic surgery group and conditional laparoscopic surgery group. The operation time, blood loss, the incidence of lymph node , the number of postoperative complications, the gastrointestinal function recovery time, postoperative hospital stay,the number of local recurrence and distant metastasis, survival rate and the total cost of hospitalization will be evaluated to confirm the feasibility of single incision laparoscopic surgery is effective and economical. It is worthy of clinical application.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
Patients undergo single incision laparoscopic surgery
Patients undergo conventional laparoscopic surgery
ruijin hospital North
Shanghai, Shanghai Municipality, China
Early morbidity rate
morbidity rate 30 days after surgery
Time frame: 30 days
Operative time
Operative time(minutes)
Time frame: intraoperative
Intraoperative blood loss
Estimated blood loss(milliliters,ml)
Time frame: intraoperative
Incision length
Incision length(centimeters,cm)
Time frame: intraoperative
Lymph node detection
Lymph nodes harvested(numbers)
Time frame: 14 days after surgery
Incisal margin
Length of proximal and distal margin (centimeters,cm)
Time frame: 14 days after surgery
Tumor size
The diameter of tumors(centimeters,cm)
Time frame: 14 days after surgery
Length of stay
Duration of hospital stay(days after surgery)
Time frame: 1-14 days after surgery
Postoperative recovery course
Time to first ambulation, flatus, liquid diet and soft diet (hours after surgery)
Time frame: 1-14 days after surgery
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Pain score
Postoperative pain is recorded using the visual analog scale (VAS) pain score (0-10 points)tool on postoperative day 1, 2, 3 and the day of discharge
Time frame: 1-3 days after surgery
3-year disease free survival rate
3-year disease free survival rate
Time frame: 36 months after surgery
5-year overall survival rate
5-year overall survival rate
Time frame: 60 months after surgery