Predictors of Response to Treatment for Depression

Inclusion Criteria: * Participants presenting with major depressive or persistent depressive disorder and moderate severity on the Clinical Global Impressions scale. * Participants may have comorbid externalizing or anxiety disorders. * Participants (and parents of minors) fluent in English. Exclusion Criteria: * Youth with history of treatment for substance use disorders. * Youth with intellectual or developmental disabilities (e.g., autism spectrum disorders, pervasive developmental disorders). * Youth with lifetime schizophrenia, psychosis, or mania. * Youth with severe current suicidality. * Youth taking antipsychotic medications or mood stabilizers. * Youth with recent changes in dosage of antidepressant (adolescents with change in dosage in past 30 days who otherwise meet study criteria will be asked to begin the study once dosage has been stable for 30 days). * Parent or child not fluent in English. * Youth who are unable to complete study procedures because of visual or hearing impairments. * Youth who have recently started outside therapy (past 30 days at time of intake), are engaged in treatment that is determined to be too similar to study therapy (e.g, other CBT groups), or are currently in treatment that is too intensive to allow for participation in study therapy (e.g., partial hospitalization programs)