Different Crystalloids on AKI in Shock

Southeast University, China600 enrolled

Overview

The goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Fluid resuscitation is important to shock patients. Saline is the classical fluids for resuscitation. However, studies showed that resuscitation with saline could increase the incidence of hyperchloremia and acute kidney injury. Thus, the goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Study Type

OBSERVATIONAL

Enrollment

600

Conditions

Shock

Interventions

Fluid resuscitationOTHER

Patients in the saline group were resuscitated with saline, patients in the other group were resuscitated with acetated Ringer's sodium

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Shock patients who need fluid resuscitation with risk factors of acute kidney injury Exclusion Criteria: * Patients with a history of chronic kidney injury and hemodialysis therapy

Locations (1)

Zhongda Hospital Southeast University

Nanjing, Jiangsu, China

Outcomes

Primary Outcomes

Incidence of acute kidney injury

Time frame: 28 day

Secondary Outcomes

Application of renal replacement

Time frame: 28 day

Data from ClinicalTrials.gov

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