The aim of this study is to compare the effect of different epidural initiation volumes on postoperative pain scores, local anesthetic requirements, and motor block in patients who undergo patient controlled epidural analgesia for postoperative pain after cesarean section.
90 minutes after combined epidural spinal catheter insertion, three different volumes (5 mL, 10 mL, and 20 mL) are administered with a patient-controlled epidural analgesia (PCEA) device through the epidural catheter. For each group, 0.625% bupivacain + 2 μg/mL fentanyl, is administered. The visual analog scale, first analgesic demand time, the number of PCEA requirement per hour, morphine requirement, nausea-vomiting, itching, motor block, hypotension, and total consumed analgesic, and ephedrine amounts of the patients are recorded in the recovery room and at postoperative 2, 4, 6, 12 hours.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
81
5 mL 0.625% bupivacaine + 2 μg/mL fentanyl solution is administered from epidural catheter
10 mL 0.625% bupivacaine + 2 μg/mL fentanyl solution is administered from epidural catheter
20 mL 0.625% bupivacaine + + 2 μg/mL fentanyl solution is administered from epidural catheter
Inonu University Turgut Ozal Medical Center
Malatya, Turkey (Türkiye)
Change in postoperative pain scores
Visual analog scale
Time frame: up to 12 hours after cesarean delivery
First analgesic demand time
Time to first analgesic requirement (first patient controlled epidural analgesic demand time)
Time frame: up to 12 hours after cesarean delivery
The number of analgesic requirement
The number of patient controlled epidural analgesic requirement per hour
Time frame: up to 12 hours after cesarean delivery
Morphine requirement
Intravenous morphine administration
Time frame: up to 12 hours after cesarean delivery
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