The purpose of this study was to investigate the salivary levels of inflammatory and their association with oral health in xerostomía patient
Primary Outcome Measures: * salivary Proinflammatory and anti-inflammatory cytokines * questionnaire is provided to the patient for xerostomia characterization Secondary Outcome Measures: * Probing pocket depth * Probing pocket depth and clinical attachment level * Gingival index * Plaque index * Bleeding on probing
Study Type
OBSERVATIONAL
Enrollment
30
IFN-, IL-10, IL-1b, IL-4 and IL-6
Pia Lopez Jornet
Murcia, Spain
Pia Lopez Jornet
Murcia, Spain
saliva flow rate
Unstimulated salivary flow rate. Pathological \< or 1.5 ml/ 15 minutes.
Time frame: 2 months
Xerostomia
Visual Analogue Scale (VAS) for xerostomia severity (0 cm: no xerostomía , 10cm : very severe xerostomia ).
Time frame: 2 months
Interleukins
Analytes in saliva IFN-(pg/ml), IL-10(pg/ml), IL-1b(pg/ml), IL-4 (pg/ml)and IL-6 (pg/ml)
Time frame: 2 months
Oral Exam
Caries number, natural teeth number
Time frame: 4 months
Periodontal evaluation
periodontal( gingival index, bleeding index, clinical attachment level, probing depth,number dental implant .A periodontal probe will be inserted between the tooth and the gum in the gingival sulcus and a measurement of the pocket depth will be measured by a trained dentist in all subjects according to American Academy of Periodontology classification of periodontal diagnosis
Time frame: 4 months
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