Intravenous Iron May Increase Depression Among Hemodialysis Patients

Benha University112 enrolled

Overview

the aim of this study is to assess whether increased ferritin after intravenous iron therapy will lead to increased prevalence of major depression among treated patients.

Study Type

OBSERVATIONAL

Enrollment

112

Conditions

Depression Hemodialysis Complication Iron Deficiency Anemia

Interventions

Intravenous iron therapyOTHER

each patient with iron def anemia received an IV syringe of iron sucrose 100 mg every dialysis session for 10 doses

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. age was above 19 years, 2. patient on maintenance hemodialysis, 3. patient had iron deficiency anemia (ferritin \> 100 ng/ml) Exclusion Criteria: 1. patient has history of depression or already using antidepressant medication, 2. Lack of ferritin level increase ≥ 50% from baseline level before IV iron administration, 3. patient already on oral or intravenous iron supplement

Outcomes

Primary Outcomes

Change in patient health questionnaire-9 score

change in patient health questionnaire-9 score before and after intravenous iron therapy

Time frame: on day 0 of start of intravenous iron and 1 week after completion of intravenous iron

Data from ClinicalTrials.gov

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