In this study, we aim to evaluate the feasibility of anti-PSMA labelling to detect post-operative prostatic tissues by two ex vivo fluorescence techniques. We will evaluate the feasibility and detection of anti-PSMA labelling by: 1. / the FEMTO-ST institute medical device, 2. / the confocal microscope that will be used to measure fluorescence spectra of biological samples.
For this protocol, 12 patients will be included.
Study Type
OBSERVATIONAL
Enrollment
8
All subjects of the study are going to have a radical prostatectomy. The FEMTO-ST medical device is used on 3 fresh biopsies (2 healthy and 1 malignant) which will be prelevated from the resected prostate in order to determine the prostatic or non-prostatic nature of tissue.
Grenoble Alpes University Hospital - Urology department
Grenoble, France
Grenoble Alpes University Hospital
Grenoble, France
Comparison of the fluorescence obtained using the FEMTO-ST device and the confocal microscope of anti-PSMA marked fresh prostate biopsies, for prostatic and non-prostatic tissue, as identified by anatomo-pathology (gold standard).
Fluorescence measurements obtained using the FEMTO-ST medical device and the confocal microscope.
Time frame: 14 months
Comparison of the fluorescence obtained using the FEMTO-ST device and the confocal microscope of anti-PSMA marked fresh prostate biopsies, for cancerous and non-cancerous tissue, as identified by anatomo-pathology (gold standard).
Fluorescence measurements obtained using the FEMTO-ST medical device and the confocal microscope.
Time frame: 14 months
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