Effect of Intrathecal Morphine in Children Undergoing Major Abdominal Surgeries,

Assiut University45 enrolled

Overview

safety and efficacy of intrathecal morphine in post operative pain relief in pediatric patients undergoing major abdominal cancer surgeries using different doses of intrathecal morphine (2 μg/kg , 5 μg/kg ,10 μg/kg).

After obtaining approval of the local ethics committee of faculty of medicine, Assiut University , Assiut , Egypt , and parent's written informed consent, This randomized double -blinded prospective study conducted on ( 45 ) pediatric patients aged 3-12 years , weighting between 10-30 kg , and of American Society of Anesthesiologists (ASA) physical status I and II scheduled for major abdominal surgeries

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Major Abdominal Surgeries

Interventions

Intrathecal MorphineDRUG

Intrathecal administration of Morphine in children undergoing major abdominal surgeries

Eligibility

Sex: ALLMin age: 3 YearsMax age: 12 Years

Medical Language ↔ Plain English

Inclusion Criteria * weight between 10-30 kg , * American Society of Anesthesiologists (ASA) I - II * major abdominal surgeries Exclusion Criteria * Children with sacral bone abnormalities * spina bifida * coagulopathy * mental delay or retardation

Locations (1)

South Egypt Cancer Institute

Asyut, Egypt

Outcomes

Primary Outcomes

visual analog scale

0- 10 in cm score range will be used to assess pain

Time frame: 24 hours postoperative .

Secondary Outcomes

rams y sedation score

0-4 score will be used

Time frame: 24 hours

Data from ClinicalTrials.gov

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