In this study physiological data is measured using wearable sensors as well as hormonal and ultrasound measurements of growing follicles/ ovulation in a group of endocrinologically healthy women with regular cycles, who aim for a spontaneous pregnancy. These women were recruited to generate reliable data on changes of the measured physiological parameters in a healthy menstrual cycle, as well as to evaluate physiological changes associated with early pregnancy. All pregnancies beginning during the study period are to be monitored to their natural end, in order to evaluate how the same nine physiological parameters are changing during pregnancy, how strong the variations of the parameters during pregnancy are, and whether they could be associated with early onsets of pregnancy complications such as premature birth or pre-eclampsia. This will be highly valuable to develop study protocols for the specific evaluation of the screening potential of pregnancy complications.
Study Type
OBSERVATIONAL
Enrollment
194
Ava is a fertility monitoring bracelet that collects various physiological parameters
Clinic for Reproductive Endocrinology
Zurich, Switzerland
Correlation between the physiology and the menstrual cycle dynamics
Correlation between a the following physiological parameters (individually or in combination), pulse rate, respiration, skin conductance response, sleep duration and quality, and skin perfusion with the menstrual cycle dynamics
Time frame: November 2016 - November 2020
Correlation between the physiology measured using a wearable device and the occurrence of pregnancy
Correlation between the following physiological parameters (individually or in combination), pulse rate, respiration, skin conductance response, sleep duration and quality, and skin perfusion with the occurrence of pregnancy.
Time frame: November 2016 - November 2020
Correlation between physiology and pregnancy complications
Time frame: November 2016 - November 2020
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