Salivary diagnostic testing is emerging as a less invasive, inexpensive alternative to serum analyte measurements with proven diagnostic accuracy in clinical settings. This study aims to continue analyzing aspects of the performance of salivary hormone competitive immunoassays for monitoring patient's reproductive hormone profiles in the reproductive cycle. Hormone levels will be monitored during treatment cycles for infertility.
This study will be a prospective study to measure salivary and serum estrogen and progesterone levels in subject's voluntarily undergoing monitored infertility treatment cycles including controlled ovarian stimulation (COS) with oral agents or gonadotropins and controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF). Ultimately, the potential applicability and reliability of salivary steroid monitoring in IVF cycles will be assessed.
Study Type
OBSERVATIONAL
Enrollment
300
Boston IVF
Waltham, Massachusetts, United States
Measurement of multiple Progesterone levels as an aid during an IVF cycle
To determine if collecting multiple salivary Progesterone levels versus a single serum hormone sample could assist in predicting the administration of Human Chorionic Gonadotropin (HCG) during an IVF cycle.
Time frame: 1 month
Measurement of salivary Estradiol level as an aid during fertility treatment
Comparison of salivary reproductive hormone values versus serum collection to see if there is a correlation between the two methods of collection.
Time frame: 1 month
Measurement of salivary Progesterone level as an aid during fertility treatment
Comparison of salivary reproductive hormone values versus serum collection to see if there is a correlation between the two methods of collection.
Time frame: 1 month
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