A Study to Evaluate the Efficacy of CV-MG01 (Myasterix) in Myasthenia Gravis

Inclusion Criteria: * Male or female Patient, with generalised myasthenia gravis (Grades 2, 3 and 4a) as per myasthenia gravis foundation of America (MGFA) classification system. * Quantitative Myasthenia Gravis (QMG) score of 10 or greater at screening and baseline. * Age of minimum 18, at the time of the consent form signature. * Patient with documented positive antibodies to AChR in one of the available validated laboratory test. * Patient may use corticosteroid treatment initiated for at least 3 months before screening, equivalent to a daily dose of 30mg prednisone as maximum, and stable (+/- 5mg change) at least 1 month before the screening and up to the first injection. * Patient may use one or two immunosuppressive drugs (initiated for a least 6 months) with or without concomitant use of corticosteroid, providing that the dosage has been stable/unchanged for 3 months before the screening and up to the first injection. * Venous access sufficient to allow blood sampling as per the protocol. * Are reliable and willing to make themselves available for the duration of the study and are willing to follow study procedures. * Have given written informed consent approved by the relevant Ethics Committee (EC) governing the site. Exclusion Criteria: * MG patients of Grade 5 based on myasthenia gravis foundation of America (MGFA) classification. * Patients with history or presence of a primary or recurrent malignant disease including the presence or history of a thymoma. * Thymectomy planned during Part A of the study period or performed within 1 year prior to the first dose of study. * Any confirmed or suspected immunosuppressive or immunodeficient condition not related to the treatment of MG, including human immunodeficiency virus (HIV) infection, or a family history of congenital or hereditary immunodeficiency. * History or evidence of administration of immunoglobulins and/or any blood products within 3 months prior to the first dose of study drug, or a planned administration of immunoglobulins during the first 3 months of the study. * History or evidence of rituximab treatment within 6 months prior to first dose of study. * History or evidence of plasmapheresis within 3 months prior to the first dose of study, or a planned plasmapheresis during the first 3 months of the study. * At high risk for aspiration. * Pulmonary: forced vital capacity reduced to less than 70% of predicted capacity. * History of severe allergic disease or reactions likely to be exacerbated by any component of the vaccine. * History or evidence of Lambert-Eaton myasthenic syndrome, drug-induced myasthenia gravis, hereditary forms of myasthenic syndrome. * History of relevant chronic degenerative, psychiatric, or neurological disorder other than MG. * Severe hepatic, renal or cardiac insufficiency or uncontrolled hypertension * Major congenital defects or serious chronic illness other than MG. * Positive pregnancy test or desire to become pregnant during the study. * Female patients of child-bearing potential that do not use a reliable and highly effective method of contraception (see Section 7.2 Contraception) at least one month before first injection, during the study and until the end of Part A. * Any significant out-of-range Clinical Laboratory results considered as clinically significant and that prevent Subject's participation into the study according to Investigator's judgment. * Previous completion or withdrawal from this study or study CV-0002. * Sponsor employees or Investigator site personnel directly affiliated with this study, and their immediate families. Immediate family is defined as a spouse, parent, child or sibling, whether biological or legally adopted. * Any medical condition or concomitant medication that, in the opinion of the Investigator, might interfere with the subject's participation in the study, poses any added risk for the subject, or confounds the assessment of the subjects.