Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance in Adults

Assiut University150 enrolled

Overview

Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit. Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement. Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Brain Tumor

Interventions

Magnetic resonance imaging with contrastDEVICE

injection of gadolinium contrast then acquisition of images with magnetic resonance imaging then spectroscopy

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

1. Inclusion criteria: \* An intra axial space occupying lesion/lesions detected on conventional structural imaging 2. Exclusion criteria: * MRI contraindications (as pace maker or claustrophobia). * Contrast hypersensitivity * Impaired renal function. * Pediatric age group

Locations (2)

Ahmed Abbas

Assiut, Cairo Governorate, Egypt

RECRUITING

Assiut Faculty of Medicine

Asyut, Egypt

RECRUITING

Outcomes

Primary Outcomes

Number of patients with malignant masses

sensitivity of the magnetic resonance spectroscopy in diagnosis of brain malignant masses

Time frame: 1 hour

Central Contacts

Ahmed Abbas, MD

CONTACT

00201003385183 bmr90@hotmail.com

Data from ClinicalTrials.gov

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