Effects of Physical Training and Isoflavone Supplementation On Pelvic Floor in Women in the Postmenopausal Period

Federal University of Uberlandia22 enrolled

Overview

This study evaluates the effect of Physical Training and Supplementation of Isoflavone About Pelvic Floor Musculature in Women in the Postmenopausal period, and it has two groups the intervetion.

The practice of physical exercise and isoflavone supplementation are ways of treating symptoms of climacteric, there is a lack of evidence as to whether these therapeutics when associated are useful for improving the strength, function, contraction pressure, electrical activity of the pelvic floor musculature of women in the Postmenopausal period.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Pelvic Floor

Interventions

ExerciseOTHER

The training program consisted of aerobic and resisted combined physical exercises performed during 10 weeks, three times weekly with 45 minutes sessions: 5 minutes of warm-up on treadmill, 20 minutes of aerobic exercises and 20 minutes of resistance exercises.

isoflavoneOTHER

Daily supplementation in 1 capsule per day of 100mg of isoflavones (containing 3.3% genistein, 93.5% dadzein and 3.2% glycitein).

placeboOTHER

Daily supplementation in 1 capsule per day containing starch of corn.

Eligibility

Sex: FEMALEMin age: 50 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy postmenopausal woman * to be able to practice exercises on treadmill and weight exercises * without physical complications that prevent the execution of physical exercises * have no history of cardiovascular disease, diabetes, renal pathologies or hypertension * Present ability to contract the pelvic floor muscles Exclusion Criteria: * Smokers * Use hormone therapy or isoflavone * Use drugs that interfere with lipid and antihypertensive metabolism * Presence of cognitive impairment or neurological condition that could affect muscle activation * Present urinary tract infection at the time of data collection * Training pelvic floor muscle

Outcomes

Primary Outcomes

The change vaginal squeeze pressure

The vaginal squeeze pressure was measured through Perineometer.To obtain the measurements, the subjects remained positioning and vaginal sensor was introduced into the vaginal cavity. The women were oriented and motivated verbally to perform three voluntary maximal contractions sustained for five seconds and one minute interval between them. Outcome Measure of the vaginal squeeze pressure is cmH20 or Pascal.

Time frame: before and after the intervetion ( 10 weeks)

The change Muscle function

"PFM" evaluation was performed by vaginal palpation .During vaginal palpation the physiotherapist introduced the index and middle fingers about 4cm inside the vagina, and requested to hold the maximum contraction of the "PFM". Muscle function was classified by the Oxford Scale Modified that five grades of the force.

Time frame: before and after the intervetion (10 weeks)

The change electromyography pelvic floor

"PFM" electromyographic activity was collected during the resting to normalize the EMG data. No instruction regarding "PFM" contraction was given during the resting of the eight seconds. After, the volunteers were instructed to perform a maximal voluntary "PFM" contraction with the instruction to move "inward and upward" with the greatest possible force and to hold the contraction for five seconds. The women were oriented and motivated verbally to perform three voluntary maximal contractions sustained for five seconds and one minute interval between them.

Time frame: before and after the intervetion (10 weeks)

Data from ClinicalTrials.gov

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