Laser speckle contrast imaging (LSCI) allows real-time, non-invasive, quantitative measurements of regional blood flow. The aim of this prospective observational study was to evaluate the blood flow changes by LSCI after peripheral nerve block and determine whether this novel optical technique can be used as a reliable indicator of successful blocks.
Methods: One hundred adult patients scheduled for elective upper or lower limb surgery with peripheral nerve block will receive LSCI measurements and pinprick sensory tests before the block and at 5-min intervals till 30 min after the block. The sensitivity, specificity of LSCI as a diagnostic method will be determined by receiver operator characteristic analysis. Clinical Implications: LSCI with quantitative data could be used as an indicator of successful blocks.
Study Type
OBSERVATIONAL
Enrollment
110
Tongji Hospital
Wuhan, Hubei, China
diagnostic power of LSCI and pinprick sensory tests for predicting successful and failed blocks
sensitivity and specificity
Time frame: at 5-min intervals till 30 min after regional block
blood flow index
perfusion unit(PU)
Time frame: 5 min before regional block and at 5-min intervals till 30 min after regional block
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.