Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth

Erzincan University60 enrolled

Overview

this study was planned to investigate the antiinflammatory activity of preemptive intravenous ibuprofen on inflammatory complications such as edema and trismus after third molar tooth surgery

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Trismus Edema

Interventions

arvelesDRUG

800 mg ibuprofen and 50 mg dexketoprofen in 150 cc normal saline before operation will be given in 30 minutes. The edema size, mouth opening (trismus) will be recorded in all patients in the preoperative period, postoperative period, postoperative 48th hour and 1 st week.

intrafenDRUG

800 mg ibuprofen in 150 cc normal saline before operation will be given in 30 minutes.The edema size, mouth opening (trismus) will be recorded in all patients in the preoperative period, postoperative period, postoperative 48th hour and 1 st week.

placebosOTHER

150 cc normal saline before operation will be given in 30 minutes.The edema size, mouth opening (trismus) will be recorded in all patients in the preoperative period, postoperative period, postoperative 48th hour and 1 st week.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Elective 3. Molar tooth extraction * Patients between the ages of 20-35 * Patients who are symptomatic * 3\. Molar tooth angular or horizontal settled patients Exclusion Criteria: * Patients who refuse to participate in the study * Patients under 20 years old, over 35 years old * Patients who are allergic to known non-steroidal anti-inflammatory drugs * Pregnant patients * Patients with severe hepatic insufficiency * Patients with severe renal insufficiency

Locations (1)

Erzincan University

Erzincan, Turkey (Türkiye)

Outcomes

Primary Outcomes

Edema size measured by tape measure method

the effect of preemptive intravenous ibuprofen on postoperative edema size

Time frame: 6 month

Secondary Outcomes

Maximum mouth opening measured with vernier caliper

the effect of preemptive intravenous ibuprofen on postoperative trismus rate

Time frame: 6 month

Data from ClinicalTrials.gov

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