Hepatectomy With or Without the Thoraco-abdominal Approach

University of Milan744 enrolled

Overview

The performance of hepatectomy for liver tumors using the thoraco-abdominal approach (TAA) versus the abdominal approach (AA) is still debated. The aim of the study is the analysis of the perioperative outcome of patients operated with or without the TAA for liver tumors.

The prospectively maintained database was queried. A 1:1 propensity score-matched analysis was applied. Among 744 patients, 246 undergoing hepatectomy with TAA and 246 undergoing hepatectomy with AA were compared. These patients were matched for baseline characteristics, underlying liver disease, comorbidity, tumor features, and extent of the resection. The rates of morbidity and mortality were the study endpoints.

Study Type

OBSERVATIONAL

Enrollment

744

Conditions

Surgery Liver Tumors Hepatectomy Liver Resection

Interventions

HepatectomyPROCEDURE

Surgery for liver tumors is the removal of a part of the liver affected by a tumor.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * First liver surgery; * Any type of malignant liver tumor, including hepatocellular carcinoma on cirrhosis. Exclusion Criteria: * Previous history of liver surgery; * Any type of benign liver tumor; * Incomplete clinical, surgical, pathological or postoperative data; * Patients treated with radiofrequency ablation alone or in combination with surgery were also excluded.

Outcomes

Primary Outcomes

Short-term outcome: Occurrence of postoperative complications or death after surgery

Occurrence of postoperative complications or death after surgery

Time frame: Within 90-days after the operation

Data from ClinicalTrials.gov

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