Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites

Inclusion Criteria: * Confirmed diagnosis of liver cirrhosis * Recurrent and refractory ascites * Patients with an age between 18 and 65 years old * Child-Pugh ≤12 * Absence of hepatic encephalopathy * Patient is willing and able to comply with all study protocol requirements, including specified follow-up and testing. * Patient, or legal authorized representative, is willing to provide written informed consent prior to enrollment in the study Exclusion Criteria: * With more than 6 paracenteses within the last 3 months * patients expected to receive transplants within the next 6 months or on waiting list * Usual contra-indication for TIPS: congestive heart failure NYHA\>III or medical history of pulmonary hypertension, portal vein thrombosis（\>50%）, hepatic polycystosis, intra-hepatic bile ducts dilatation * Patient has had previous TIPS placement * Severe liver dysfunction by: Prothrombin index \< 40% or total bilirubin \> 50μmol/l * Serum creatinine \>133μmol/l * Severe hyponatremia \<125mmol / L * Uncontrolled sepsis * Gastrointestinal hemorrhage within 6 weeks of randomization * Known allergy to albumin * Pregnant or breast feeding women * Refusal to participate or patient unable to receive informations or to sign written informed consent