The Role of Stem Cells on Immune Cells in the Development of Cardiovascular Diseases

Inclusion Criteria: * Age ≥18 and ≤75 years * With or without significant coronary artery disease on CCTA * Written informed consent Exclusion Criteria: * Chronic infections * Diabetes mellitus * Medical history of any disease associated with immune deficiency * Clinically significant infections within 3 months prior to study entry * Recent hospital admission or surgery with general anaesthesia * Known chronic kidney or liver disease * Previous vaccination within 3 months prior to study entry * Inability to personally provide written informed consent * Inability to undergo PET-CT scanning * Chronic use of anti-inflammatory drugs such as NSAIDs * History of haematological malignant disease * Documented bleeding diathesis or thrombocytopenia * Pregnancy