The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl.
The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl. The study evaluates pain scores, opioid utilization and patient satisfaction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
1
General anesthesia will be delivered per standard procedure. General anesthesia will include induction with propofol 1-3mg/kg followed by placement of a laryngeal mask airway with maintenance anesthesia of sevoflurane 0.5-1 minimum alveolar concentration (MAC).
Neuraxial anesthesia will be performed at the L2-3 or L3-4 interspace with a 25-gauge Whitacre needle in the sitting position. After free flow of cerebrospinal fluid (CSF), 40-45mg of 2-chloroprocaine will be injected based on patient's height and discretion of attending anesthesiologist, needle withdrawn and the patient placed supine.
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Pain score
Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable.
Time frame: Discharge from post anesthesia care unit (PACU) (usually one hour)
Pain score
Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable.
Time frame: Post operative day one
Pain score
Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable.
Time frame: One month postoperatively
Pain score
Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable.
Time frame: Three months postoperatively
Opioid utilization
Opioid utilization based on amount of opioid medications administered
Time frame: Surgical completion to PACU discharge (usually one hour)
Opioid utilization
Opioid utilization based on number of pain pills taken
Time frame: Postoperative day one
Opioid utilization
Opioid utilization based on average number of pain pills taken per day
Time frame: One month postoperatively
Opioid utilization
Opioid utilization based on average number of pain pills taken per day
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Time frame: Three months postoperatively
Patient satisfaction with anesthetic
Patient satisfaction with anesthetic based on 10-item patient satisfaction survey validated for regional and general anesthesia
Time frame: 24 hours after PACU discharge