Influence of Remifentanil on Postoperative Sore Throat in Patients Undergoing General Anesthesia

Keimyung University Dongsan Medical Center92 enrolled

Overview

This investigation is planned to compare the incidence and severity of postoperative sore throat according to the dose of remifentanil.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Hip Arthroplasty

Interventions

Endotracheal intubation using laryngoscopePROCEDURE

Endotracheal intubation was done using laryngoscope for general anesthesia.

High remifentanilDRUG

Remifentanil was started as 0.25 mcg/kg/min. Remifentanil dose was adjusted to maintain blood pressure (20% of preoperative blood pressure) and bispectral index (40-60) by 0.05 mcg/kg/min.

Low remifentanilDRUG

Remifentanil was administered as 0.1 mcg/kg/min.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I-III * Patients scheduled for general anesthesia with endotracheal intubation Exclusion Criteria: * Difficult airway * Rapid sequence induction * Recent sore throat * Recent upper respiratory infection * Asthma * Chronic obstructive pulmonary disease * Chronic cough * Pregnancy * Allergy to remifentanil * Friable teeth * History of head and neck surgery * Multiple intubation attempts * Regional anesthetic agents * Gastric tube * Dexamethasone

Locations (1)

Keimyung University

Daegu, Non-US/Canada, South Korea

Outcomes

Primary Outcomes

Number of participants with sore throat

Time frame: At 24 hr