Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery

Inclusion Criteria: 1. Undergoing unilateral cataract extraction and implantation of a monofocal IOL (at the time of enrollment) 2. Age 18 to 85 years 3. Receive, understand, and sign a copy of the written informed consent form (ICF) 4. Are able to return for all study visits and willing to comply with all study-related instructions Exclusion Criteria: 1. Are undergoing implantation of a multifocal and/or depth enhancing IOL 2. Are undergoing or have just undergone cataract surgery on the study eye that is deemed complex or may require manipulation of the iris 3. The study eye has a small pupil or iris requiring manipulation due to synechiae and/ Tamsulosin (Flomax®, Boehringer Ingelheim) use 4. Have a Seidel positive wound following surgical procedure despite suture and/or ReSure® Sealant placement 5. Have had ocular surgery of any kind in the study eye within 3 months prior to baseline visit (Day 0) 6. Have undergone cataract surgery in the fellow eye within 4 weeks prior to baseline visit (Day 0) and still require post-operative medications in that fellow eye 7. Are scheduled for surgery in the fellow eye within the study period 8. Have anterior chamber inflammation as measured by slit lamp examination in the study eye at the baseline visit (Day 0) \[Defined as anterior chamber (AC) cell and/or flare grade \> 0\] 9. Have history of uveitis or inflammatory disease in the study eye 10. Requires simultaneous supplemental surgery, such as glaucoma procedures or vitrectomy, in the study eye 11. Have used any topical ocular medication in either eye, other than tear substitute for dry eye, within the past 2 weeks prior to baseline visit (Day 0) 12. Have used topical corticosteroid or nonsteroidal anti-inflammatory drug (NSAID) treatment in either eye \< 48 hours prior to the baseline visit (Day 0) (excluding the use of topical NSAIDs, pre-operatively on Day 0 and administered at the clinic site under the investigator's oversight) 13. Have IOP ≥ 25 mmHg at baseline, a history of glaucoma, and/or require ocular anti-hypertensive medications 14. Are known corticosteroid IOP responder in study eye 15. Have received systemic administration of corticosteroid and/or immunosuppressants within the past 14 days prior to baseline visit (Day 0) 16. Have received intravitreal, sub-Tenon, or any periocular corticosteroid treatment in either eye within the past 6 months prior to baseline visit (Day 0) 17. Have open wounds/skin disease on the forehead area where the iontophoresis return electrode will be applied 18. Have lesions of the eyelids or the ocular surface impeding the application of the iontophoresis applicator 19. Have blepharospasm, blepharophimosis, or other eyelid anatomic variations precluding placement of the iontophoresis applicator 20. Have known allergy to dexamethasone or dexamethasone phosphate or any medication to be used in this study 21. Have history or diagnosis of ocular herpes, corneal lesion of suspected herpetic origin that could be worsened with steroid use 22. Have optic neuritis of any origin 23. Have clinically suspected or confirmed central nervous system or ocular lymphoma 24. Have active hyphema, pars planitis, choroiditis, toxoplasmosis scar, vitreous hemorrhage, and/or clinically significant macular edema (CSME) that would compromise visual acuity recovery 25. Have severe/serious ocular pathology or medical condition which may preclude study completion 26. Have pacemaker and/or any other electrical sensitive support system 27. Are pregnant or lactating female, or female of childbearing age and using inadequate birth control method 28. Have participated in another investigational device or drug study within 30 days of baseline visit (Day 0) (other clinical trial participation while participating in EGP-437-009 would be prohibited per protocol) 29. Have previously participated in a study with EGP-437