Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
Guided tissue regeneration (GTR) combined with CGF and bone graft to treat mandibular furcation involvements
CGF combined with bone graft to treat mandibular furcation involvements
Peking university School and Hospital of Stomatology
Beijing, Beijing Municipality, China
RECRUITINGclinical measurement
Probing depth
Time frame: 1 year
clinical parameter
clinical attachment loss
Time frame: 1 year
radiographic parameter
cone beam computerized tomographic scanning
Time frame: 1 year
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