Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Universidade Federal de Pernambuco35 enrolled

Overview

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Healthy Aging

Interventions

Whole Body VibrationOTHER

A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Elderly individuals aged between 60 and 80 years * Young individuals aged between 18 and 30 years * Able to walk without assistance * Good understanding to perform the proposed procedures * Sedentary or low active Exclusion Criteria: * Body Mass Index (BMI) \> 35Kg/m2 * Systolic blood pressure \> 140 mmHg or diastolic blood pressure \> 90 mmHg (at rest) * Difficulty adapting to the whole body vibration * Smoking * Neuromuscular or degenerative disorders * Neurological diseases * Cardiopulmonary comorbidities * Cardiac arrhythmias * Osteoarticular disorders * Use of hormone replacement therapy * Use medications or supplements known to affect cardiovascular parameters * Labyrinthitis

Locations (1)

Federal University of Pernambuco

Recife, Pernambuco, Brazil

Outcomes

Primary Outcomes

Autonomic Function

Heart rate variability will be assessed from 3-channel holter

Time frame: Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes

Secondary Outcomes

Sympathetic modulation

Sympathetic modulation will be assessed from 3-channel holter

Time frame: Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes

Parasympathetic modulation

Parasympathetic modulation will be assessed from 3-channel holter

Time frame: Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes

Sympathovagal Balance

Sympathovagal Balance will be assessed from 3-channel holter

Time frame: Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes

Heart Rate

Non-invasive measures will be assessed from 3-channel holter

Time frame: Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes

Blood pressure

Non-invasive measures of brachial blood pressure

Time frame: Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes

Peripheral oxygen saturation

Non-invasive measures will be assessed from pulse oximeter

Time frame: Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes

Adverse effects

Data from ClinicalTrials.gov

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