Anterior cruciate ligament (ACL) rupture is one of the most common sports-related knee injuries. Because it is such a significant injury - requiring a long period of rehabilitation before the injured person is ready to return to physical activity, the burden of injury is high. This can help to explain why so much of orthopaedic research is devoted to evaluating the outcomes of ACL injury. However, while there has been extensive study of short-term (up to 5 years after injury) outcomes, few studies have followed patients beyond 15 years after their ACL injury. This is important because long-term follow-up can provide key insights to guide the information provided to newly injured patients (e.g. to help set realistic expectations of what the injured person can expect of their knee function in the future), and help us evaluate the efficacy of previous treatments. The primary aim is to assess the influence of an acute ACL injury on knee function and quality of life, 32-37 years after the index injury. Approximately 300 patients injured between 1980 and 1985 will be invited to participate in the study. Patient- and clinician-reported outcomes, and radiographic osteoarthritis will be evaluated.
Patients injuring their ACL between 1980 and 1985 have periodically been followed since the injury. Now, we plan to contact all patients and invite them to participate. The patients will be asked to 1. complete a questionnaire battery 2. visit the movement laboratory at Linköping University for an objective assessment of knee function and 3. have an x-ray of both knee joints. Baseline information including associated injuries, treatment and activity level exist for all the patients. At that time, rehabilitation was normally completed after 4-6 months for non-operatively treated patients, and nine months after ACL surgery.
Study Type
OBSERVATIONAL
Enrollment
300
Surgical initial ACL treatment
Non surgical initial ACL treatment
Linkoping University
Linköping, Östergötland County, Sweden
RECRUITINGSelf reported knee function
Knee Injury and Osteoarthritis Outcome Score, KOOS 4 (Pain, Symptoms, Sport/Rec, QOL subscales)
Time frame: 32-37 years after ACL injury
Osteoarthritis
Development of osteoarthritis examined with tibiofemoral and patellofemoral radiographs
Time frame: 32-37 years after ACL injury
Quality of life
ACL-Quality of Life scale (ACL-QoL)
Time frame: 32-37 years after ACL injury
Physical activity
Total time over the previous week spent doing moderate, and vigorous activity AND accelerometer measures
Time frame: 32-37 years after ACL injury
Objective assessment of knee function
Concentric isokinetic muscle strength
Time frame: 32-37 years after ACL injury
Objective assessment of knee function
Functional testing; stand-up test
Time frame: 32-37 years after ACL injury
Objective assessment of knee function
Functional testing; hopping performance in one leg hop for distance
Time frame: 32-37 years after ACL injury
Objective assessment of knee function
Postural control (one leg stand test)
Time frame: 32-37 years after ACL injury
Associated injuries and additional surgery
Patient reported
Time frame: 32-37 years after ACL injury
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