This is a registry study in adult patients with newly diagnosed or refractory/relapsed acute myeloid leukemia. Investigator's sites: 60 sites in Germany. Primary objectives: * Identification of epidemiological data on AML: age, prognostic factors and subgroup distributions. Incidence and age distribution are compared with the data of population-related tumor registry. * Evaluation of the most important patient-relevant clinical endpoints (outcomes): relapse-free survival (RFS) / time to relapse (TTR), calculation of cumulative incidence of relapse (CIR) and overall survival (OS) * Documentation of treatment strategy
see brief summary
Study Type
OBSERVATIONAL
Enrollment
15,000
Klinikum Mittelbaden
Baden-Baden, Baden-Wurttemberg, Germany
RECRUITINGUniverstitätsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, Germany
RECRUITINGKlinikum Mannheim GmbH
Mannheim, Baden-Wurttemberg, Germany
RECRUITINGDiakonie-Klinikum
Schwäbisch Hall, Baden-Wurttemberg, Germany
RECRUITINGKliniken Sindelfingen-Böblingen gGmbH
Sindelfingen, Baden-Wurttemberg, Germany
RECRUITINGRobert-Bosch-Krankenhaus GmbH
Stuttgart, Baden-Wurttemberg, Germany
RECRUITINGRems-Murr-Klinikum Winnenden
Winnenden, Baden-Wurttemberg, Germany
RECRUITINGKlinikum Augsburg
Augsburg, Bavaria, Germany
RECRUITINGSozialstiftung Bamberg
Bamberg, Bavaria, Germany
RECRUITINGKlinikum Bayreuth GmbH
Bayreuth, Bavaria, Germany
RECRUITING...and 50 more locations
Epidemiological parameters
Epidemiological parameters
Time frame: 10 years
Relapse free survival (RFS)
Relapse free survival
Time frame: 10 years
Time to relapse (TTR),
Time to relapse (TTR),
Time frame: 10 years
Overall Survival (OS)
Overall Survival (OS)
Time frame: 10 years
cumulative incidence of relapse (CIR)
cumulative incidence of relapse (CIR)
Time frame: 10 years
Complete Remission (CR)
Complete Remission
Time frame: yearly follow up 10 years
Treatment related mortality (TRM)
Treatment related mortality
Time frame: yearly follow up 10 years
Therapy-associated morbidity
grade IV toxicities
Time frame: yearly follow up 10 years
Recording and evaluating the quality of therapy and diagnosis
Recording and evaluating the quality of therapy and diagnosis
Time frame: 10 years
Validation of published prognostic factors at the registry cohort and the search for new possible prognostic factors
Validation of published prognostic factors at the registry cohort and the search for new possible prognostic factors
Time frame: 10 years
Recording and describing new forms of therapy and new supportive measures
Recording and describing new forms of therapy and new supportive measures
Time frame: 10 years
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