HFCS, Apple Juice, Excess Free Fructose & asthma-the FHS-OS

Luanne R DeChristopher2,657 enrolled

Overview

Perform an exploratory analysis of association between consumption of high excess free fructose (EFF) beverages (high fructose corn syrup sweetened soft drinks, fruit drinks, apple juice) and Chronic Bronchitis (CB)/history of CB, and asthma/ history of asthma.

Study Type

OBSERVATIONAL

Enrollment

2,657

Conditions

Asthma

Interventions

Dietary intakesOTHER

Analysis of association between consumption of high excess free fructose (EFF) beverages (high fructose corn syrup sweetened soft drinks, fruit drinks, apple juice)

Eligibility

Sex: ALLMin age: 5 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Participants in the FHS Offspring who answered questions in the FFQ about soft drinks, fruit drinks and fruit juice consumption; Participants with non-missing data for the exposures and potentially confounding variables of interest. Exclusion Criteria: * Extreme energy intake on food frequency questionnaire (defined as ≤600 kcal/day or ≥4800 kcal/day)

Outcomes

Primary Outcomes

Asthma

Incident asthma defined as self-reported asthma (at each exam), including wheezing or asthma (have you had asthma/ wheeze since the last exam of short duration, long duration or with respiratory infections)

Time frame: Exams 3 - 7, 17 years of follow-up

Data from ClinicalTrials.gov

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