The Effect of Autologous Stromal Vascular Fractions on Skin Regeneration

Inclusion Criteria: * Age of 18 to 65. * No other facial plastic surgery or cosmetic surgery was performed during the study period (frontal, temporal, and lower eyelid). * Intends to undergo facial anti-aging treatment with SVF Exclusion Criteria: * Not fit for stem cells graft treatment. * Evidence of infection, ischemia, ulcer or other pathological changes within the targeting area which defined as not suitable for SVF treatment; or history of delayed healing, radiational therapy. * Significant renal, cardiovascular, hepatic and psychiatric diseases. * Significant medical diseases or infection (including but not limited to the carrier of hepatitis B virus or HIV). * Used external medication on the targeting area within 4 weeks. * Skin invasive treatment including laser on the targeting area within 6 months. * Hyaluronic acid injection on the targeting area within 12 months. * Botulinum toxin injection on the targeting area within 6 months. * History of any hematological disease, including leukopenia , thrombocytopenia, or thrombocytosis. * Evidence of malignant diseases or unwillingness to participate.