Evaluation of Efficacy of Two Therapeutic Strategies for Cervical Maturation Before Medical Termination

Inclusion Criteria: * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan * The patients is at least 18 years old * Patient with a singleton pregnancy between 14 and 34 weeks gestation with an indication for medical termination due to maternal or fetal problem as validated by pluridisciplinary prenatal diagnosis center. Exclusion Criteria: * The subject is participating in an interventional study or is in a period of exclusion determined by a previous study * The patient is under safeguard of justice * The subject refuses to sign the consent * It is impossible to give the subject informed information * Patient has vaginismus * Patient has a cervix permitting artificial rupture of membrane * Patients taking one of the following treatments, contraindicated for mifepristone: ketoconazole, itraconazole, erythromycin, grapefruit juice, rifampicin, dexamethasone, St John's wort and certain anti-convulsants (phenytoin, phenobarbital, carbamazepine). Patients contraindicated for oxytocine.