Physical Condition and Bariatric Surgery

Inclusion Criteria: * Male or Female * Age between 18 and 60 years * Body mass index: BMI\> 40 kg / m2 * Candidates for bariatric surgery Exclusion Criteria: * Subject under 18 or over 60 years of age * Biological assessment considered abnormal by the investigator * HIV serology or known positive HCV * Pregnant or nursing women * For women of childbearing age: beta-hCG positive dosage or absence of contraception deemed reliable (oral contraceptive, IUD, implant or hormonal patch) * Medical or surgical history (judged by the investigator to be inconsistent with the study) * Subject with cardiorespiratory and / or osteo-articular disorders limiting their ability to perform physical tests or training * Subject with cardiovascular or neoplastic disease * Subjects with an infection in the 3 months prior to inclusion * Hypercorticism and uncontrolled dysthyroidism * Patient with known neuro-muscular pathology: myopathy, myasthenia gravis, rhabdomyolysis, paraplegia, hemiplegia * Patient with chronic or acute inflammatory disease the 3 months before inclusion * CRP\> 20 mg / l * Person treated with or having stopped treatment for less than 3 months prior to inclusion by corticosteroids, immunosuppressant, anabolic agent, growth hormone * Person with an unstable psychiatric condition * Blood donation in the two months preceding the study * High alcohol consumption (\> 2 to 3 drinks per day depending on sex) or presence of drug addiction * Significant smoking (\> 5 cigarettes / day or equivalent in cigars or pipe tobacco) * Intense sports activity (\> 5 hours / week) * Subjects excluded from another study or having received more than 4500 € in the year following their participation in clinical studies