This registry is designed to investigate factors affecting the efficacy of Dun Ye Guan Xin Ning tablet on patients with stable angina. The potential hypothesis is that Dun Ye Guan Xin Ning has a better effect on different subgroup patients with certain characteristics.
A total of 1000 eligible patients enrolled from 20 centers will take standard medications of care for stable angina plus Dun Ye Guan Xin Ning tablet for 6 months. Symptoms, questionnaires (SAQ, PSQI, and angina pectoris quantitative table of Chinese medicine symptoms scale), lipid, fasting glucose, homocysteine, EKG, blood pressure and other physical examination will be collected at baseline and follow-up. Among them, 200 patients will measure and inflammation biomarkers and endothelial function for further evaluation.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
1,000
Dun Ye Guan Xin Ning tablet 320 mg orally every time and 3 times per day for 6 months.
Peking University First Hospital
Beijing, China
RECRUITINGAngina pectoris symptom
Improvement od angina pectoris symptom
Time frame: 6 month
Life quality
using seattle Angina Questionnaire
Time frame: 6 month
Sleep quality
using pittsburgh sleep quality index
Time frame: 6 month
Chest tightness
using angina pectoris quantitative table of Chinese medicine symptoms
Time frame: 0, 1 month, 3 month, 6 month
Biomarkers
levels of TG,TC, LDL, HDL, HCY, IL-6、TNF-α、and CRP
Time frame: 6 month
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