A Study to Investigate Two Atteris Antimicrobial Products on Chronic Wound Healing.

Inclusion Criteria: 1. Male or female between the ages of 18 and 89 2. If IDDM or NIDDM, glycosylated hemoglobin, HgbA1c, ≤10% 3. Presence of chronic Wound of any etiology between 0.5 cm2 and 15 cm2, inclusive, post debridement 4. Wound has been present for at least 4 weeks, but not greater than 52 weeks at time of screening 5. Non-surgical wounds which meet the clinical definition of chronic between 0.5 cm2 and 15 cm2 6. Adequate arterial perfusion of the affected limb, defined as at least one of the following: 1. Ankle-brachial index (ABI) ≥0.7 and ≤1.2 2. Dorsum transcutaneous oxygen test ≥ 30 mm Hg 3. Biphasic or triphasic Doppler waveforms at screening 7. Patient and/or caregiver have the ability and willingness to understand and comply with study procedures and give written, informed consent prior to enrollment in the study or initiation of study procedures. Exclusion Criteria: 1. Suspected or confirmed signs/symptoms of active wound infection or gangrene 2. Hyperbaric Oxygen Therapy, any duration, within the past 12 months 3. Osteomyelitis 4. Use of oral or IV antibiotic/antimicrobial agents within 2 days (48 hours) of baseline 5. Subjects who have received growth factor therapy (e.g., autologous platelet-rich plasma gel, becaplermin,) within 28 days of screening 6. Subjects who have received dermal substitutes (e.g. Integra, collagen, micronized cadaver skin, bilayered cell therapy, dermal substitute, extracellular matrix etc.) within 28 days of screening. 7. Pyoderma gangrenosum, or Reynaud's disease 8. Wound with necrotic tissue covered with slough or eschar that cannot be debrided 9. Chronic wounds with exposed bone 10. Wounds with fistulas or deep sinus tracks of unknown depth 11. Active Charcot foot on the study limb 12. Receiving hemodialysis or peritoneal dialysis 13. History of malignancy excluding non-melanoma skin cancer 14. Treatment with radiation or chemotherapy within 3 months of screening 15. Known immunosuppression, excluding diabetes mellitus 16. Receiving (within 30 days of enrollment) or scheduled to receive a medication or treatment which is known to affect wound healing, such as systemic steroids (such as daily prednisone), immunosuppressive therapy, radiation or chemotherapy of any kind, autoimmune disease therapy or cytostatic therapy 17. Subjects with known alcohol or substance abuse within 6 months of screening 18. Subjects with known allergy to PHMB, acrylate polymer and silicone 19. Pregnancy or breastfeeding at time of screening 20. Participation in another investigational device, drug, or biological trial that may interfere with results within 6 months of screening