The Effect of Popliteal Plexus Block on Pain After Total Knee Arthroplasty

Phase 4CompletedNCT03198403

Regionshospitalet Silkeborg17 enrolled

Overview

The study aims to investigate the effect of the Popliteal plexus block (PPB) on postoperative pain after total knee arthroplasty

Cadaver dissection studies have shown a spread of dye to the popliteal fossa and colored the popliteal plexus by injecting in the distal part of the adductor Canal. The popliteal plexus is formed by contribution from the tibial and the obturator nerves. Investigators hypothesized that a PPB may reduce postoperative pain after total knee arthroplasty.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Popliteal Plexus Block Total Knee Arthroplasty

Interventions

Bupivacaine-epinephrineDRUG

Popliteal plexus block with 10 mL of bupivacaine-epinephrine 5 mg/mL + 5 microgram/mL.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients undergoing total knee arthroplasty in spinal anesthesia * age \> or = 18 years * American Society of Anesthesiologists (ASA) status I-III * Informed consent Exclusion Criteria: * Patients unable to cooperate * Patients not able to speak Danish * Pregnancy * Contraindication towards ana Medical product used in the study * Preoperatively reduced sensation on the medial and lateral part of the lower leg * Patients with diabetic requiring Medical treatment * Preoperative daily intake of opioids

Locations (1)

Silkeborg Regionalhospital

Silkeborg, Denmark

Outcomes

Primary Outcomes

The percentage of patients with postoperative pain NRS

Evaluated as the percentage of patients with postoperative pain NRS \>3, dropping in pain score to NRS = or \< 3 after the PPB

Time frame: 0 - 60 minutes

Secondary Outcomes

Percentage of patients having a femoral triangle block(FTB) reporting NRS > 3

Percentage of patients having a FTB, reporting postoperative pain NRS \>3

Time frame: Pain scores every 15 minutes (from end injection FTB to NRS>3 or 3 hours after full sensation of the leg)

Onset time of PPB

Time from end of injection of PPB to NRS = or \< 3

Time frame: NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB)

Turn off time of spinal anesthesia

Time from arrival in PACU to normal cutaneous sensation (measured by a neuro-pen, sensation=point 2) on the lateral part of the thigh and lateral part of the lower leg

Time frame: Time from arrival in PACU and during maximum 6 hours

Correlation between normal cutaneous sensation and developing of pain

Correlation between normal cutaneous sensation (measured by a neuro-pen, sensation=point 2) and developing of pain (NRS\>3)

Time frame: From arrival in PACU and during maximum 6 hours

The effect of the PPB on cutaneous sensation

Tested on the lateral part of the lower leg

Time frame: NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB)

The effect of the PPB on muscle strength of the foot

Data from ClinicalTrials.gov

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