The purpose of this study is to determine whether prolonged inflation time on drug-eluting stents deployment for ST-elevation myocardial Infarction was better than conventional stents deployment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
the inflation time was more than 30 seconds when the Drug-eluting Stents deploying.The PROMUS Element Plus Stent or Co-Cr sirolimus-eluting coronary stent system（GuReater）was used in this study
the actual inflation time was within 10s determined by interventional cardiologist.The PROMUS Element Plus Stent or Co-Cr sirolimus-eluting coronary stent system（GuReater）was used in this study
West China Hospital
Chengdu, Sichuan, China
RECRUITINGNumber of Participants With TIMI 3
TIMI 0 flow (no perfusion) refers to the absence of any antegrade flow beyond a coronary occlusion.TIMI 1 flow (penetration without perfusion) is faint antegrade coronary flow beyond the occlusion, with incomplete filling of the distal coronary bed.TIMI 2 flow (partial reperfusion) is delayed or sluggish antegrade flow with complete filling of the distal territory.TIMI 3 is normal flow which fills the distal coronary bed completely
Time frame: 1 minute after sent was deployed
corrected TIMI frame count(frames)
Grading was done on cinefilm at 15frames/s made in a Philips digital coronary imaging catheterization laboratory.
Time frame: 1 minute after sent was deployed
myocardial blush grade
0, no myocardial blush or contrast density; 1, minimal myocardial blush or contrast density; 2,moderate myocardial blush or contrast density but less than that obtained during angiography of a contralateral or ipsilateral non- infarct-related coronary artery; and 3, normal myocardial blush or contrast density, comparable with that obtained during angiography of a contralateral or ipsilateral non-infarct-related coronary artery
Time frame: 1 minute after sent was deployed
Number of Participants ST-segment resolution
1, normalized, defined as no residual ST-segment elevation; 2, improved, defined as a residual ST-segment elevation ,70% of with that on the first ECG; and 3, unchanged, defined as a residual ST-segment elevation 70% of that on the first ECG
Time frame: 60min after the operation
Number of Participants Death from cardiac causes
death from acute myocardial infarction, cardiac perforation, or pericardial tamponade; an arrhythmia or conduction abnormality; complications of the interventional procedure at baseline
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Time frame: one month after the operation
Number of Participants Target-vessel revascularization
any revascularization intervention (PCI or CABG) occurring in a treated vessel at any time after the index intervention.
Time frame: one month after the operation
Number of Participants stent thrombosis
evidence of any myocardial infarction with angiographic confirmation of in-stent thrombus or unexplained death within 30 days after the procedure as stent thrombosis
Time frame: one month after the operation
Number of Participants had Major bleeding
any symptomatic intracranial hemorrhage, or clinically overt signs of hemorrhage (including imaging) associated with a drop in hemoglobin of\>= g/dL (or when the hemoglobin concentration is not available, an absolute drop in hematocrit of\>=15%)
Time frame: one month after the operation