Blood Recirculation and vvECMO

N/ACompletedNCT03200314

Charite University, Berlin, Germany21 enrolled

Overview

A prospective, observational study will be performed measuring recirculation of blood through a veno-venous Extracoporeal Membrane Oxygenation (vvECMO) in patients with acute respiratory distress syndrome (ARDS) on vvECMO. ECMO blood flow will be adjusted with respect to recirculation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ARDS Extracorporeal Membrane Oxygenation

Interventions

Measurment of blood recirculationOTHER

Ultrasound based measurments of blood recirculating through the vvECMO circuit.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients aged 18 years or older * ARDS * veno-venous ECMO Exclusion Criteria: * age \< 18 years * hemodynamic instability during measurement of recirculation * pregnancy * inability to obtain patient's consent or consent of legal guardian

Locations (1)

Charite University, Berlin, Germany

Berlin, Germany

Outcomes

Primary Outcomes

Recirculation of vvECMO blood flow

Amount of ECMO blood flow recirculating through the vvECMO circuit

Time frame: Once within first week after ICU admission during 4 hours

Secondary Outcomes

Reduction of vvECMO blood flow

Reduction of vvECMO blood flow if a significant recirculation can be measured

Time frame: Once within first week after ICU admission during 4 hours

Arterial blood oxygen content after reduction of vvECMO blood flow

Change in arterial blood oygen content after reduction of vvECMO blood flow

Time frame: Once within first week after ICU admission during 4 hours

Data from ClinicalTrials.gov

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