Ultrasonography of optic nerve sheath diameter shows a good level of diagnostic accuracy for detecting intracranial hypertension. The aim of this study is to evaluate the effect of epidural block on intracranial pressure in pediatric patients with cerebral palsy undergoing osteotomy of lower extremity. Forty patients, aged 4 years to 13 years, receiving epidural block before osteotomy will be divided into bolus group (n=20) and infusion group (n=20). Randomly selected patients of the bolus group are given 0.3 ml/kg bolus of 0.15% ripivacaine for epidural block. In contrast, patients in the infusion group are given 0.3 ml/kg/hr 0.15% ripivacaine for epidural block. The primary endpoint is the difference in the optic nerve sheath diameter after epidural block measured by optic nerve ultrasonography between groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
Randomly selected patients of the bolus group are given 0.3 ml/kg bolus of 0.15% ripivacaine for epidural block.
Randomly selected patients of the infusion group are given 0.3 ml/kg/hr 0.15% ripivacaine for epidural block.
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine
Seoul, South Korea
The difference in the optic nerve sheath diameter(ONSD) between groups
The optic nerve sheath diameter measured by optic nerve ultrasonography.
Time frame: 5 minutes before epidural block
The difference in the optic nerve sheath diameter(ONSD) between groups
The optic nerve sheath diameter measured by optic nerve ultrasonography.
Time frame: 1 second after epidural block
The difference in the optic nerve sheath diameter(ONSD) between groups
The optic nerve sheath diameter measured by optic nerve ultrasonography.
Time frame: 10 minutes after epidural block
The difference in the optic nerve sheath diameter(ONSD) between groups
The optic nerve sheath diameter measured by optic nerve ultrasonography.
Time frame: 70 minutes after epidural block
The difference in the number of patients whose ONSD values increased to more than 5.75 mm at each time point between the two groups
The optic nerve sheath diameter measured by optic nerve ultrasonography
Time frame: 5 minutes before epidural block
The difference in the number of patients whose ONSD values increased to more than 5.75 mm at each time point between the two groups
The optic nerve sheath diameter measured by optic nerve ultrasonography
Time frame: 1 second after epidural block
The difference in the number of patients whose ONSD values increased to more than 5.75 mm at each time point between the two groups
The optic nerve sheath diameter measured by optic nerve ultrasonography
Time frame: 10 minutes after epidural block
The difference in the number of patients whose ONSD values increased to more than 5.75 mm at each time point between the two groups
The optic nerve sheath diameter measured by optic nerve ultrasonography
Time frame: 70 minutes after epidural block
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.