Comparison Between TICL and ICL+AK for High Myopic Astigmatism

N/ACompletedNCT03202485

Wenzhou Medical University62 enrolled

Overview

To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Astigmatism High Myopia

Interventions

Toric Implantable Collamer LensDEVICE

uses Toric Implantable Collamer Lens implantation to correct the high myopic astigmatism.

ICL + Astigmatic keratotomyDEVICE

uses Implantable Collamer Lens implantation combined with Astigmatic keratotomy to correct the high myopic astigmatism

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age ranged from 18 to 40 years, * myopia greater than -8.00 diopters (D), and refractive cylinder in the range of 1.50D to 5.50D, * for the patients who were planned to undergo AK+ICL implantation, the axial difference between the corneal astigmatism and the manifest refractive astigmatism was less than 10 degree, * a stable refractive error during the previous 2 years, * anterior chamber depth more than 2.8 mm, * endothelial cell density (ECD) more than 2500 cells/mm2, and * scotopic pupillary diameter less than 7 mm. Exclusion Criteria: * subjects had significant irregular astigmatism, corneal pathological changes, glaucoma, ocular inflammation, or previous ocular trauma or surgery.