Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour.

N/AUnknownNCT03205020

mona nematallah58 enrolled

Overview

The aim of the current study is to assess the accuracy of maternal serum amyloid A for prediction of preterm labor in women with threatened preterm labor.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Preterm Labor

Interventions

serum amyloid a testDIAGNOSTIC_TEST

* Women who are diagnosed with preterm labor (28-36 weeks) will be enrolled in this study. Serum samples will be collected from all women before any intervention. All women will be sampled once at the time of admission. * Venous blood sample (5 c.c) will be taken from each participant for examination of serum amyloid A. * The collected blood will be centrifuging and serum will be stored to measure the level of amyloid A by (ELISA) technique in clinical pathology department- Ain shams University

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant women, age 18 - 35. * Gestational age: 28 - 36+6 weeks. * Singleton pregnancy. * No past history of any medical disorder and with no other medical complications during pregnancy * Nonsmoker. * Diagnosis of preterm labor is based on the American College of Obstetricians and Gynecologists Guidelines Criteria of preterm delivery: 1. Gestational age: 28 - 36+6 weeks 2. Presence of uterine contractions (at least 4 in 20 minutes or 8 in 60 minutes) 3. cervical dilation ≥ 4 cm 4. Cervical effacement ≥ 80%. Exclusion Criteria: * Of any patient with the following risk factors for preterm labor: * Over distended uterus . * hemorrhage * Uterine anomalies

Locations (1)

Ain Shams University

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

prevalence of Amyloid A level in women with preterm labour

venous sample will be taken from each participant from onset of labour, Amyloid a level will be calculated

Time frame: 6 months

Secondary Outcomes

neonatal complications

preterm baby will be examined at neonatal intensive care unit by neonatologist. • Admission to Neonates intensive care unit.

Time frame: 6 months

Central Contacts

mona cairo nematallah, MS

CONTACT

01061490044 drmonanematallah11@gmail.com

MONA M, MS

CONTACT

01272207585 newnononew@gmail.com

Data from ClinicalTrials.gov

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