Treatment in Patients With Globus: Psychoeducation, Anxiolytics or Proton Pump Inhibitors

Inclusion Criteria: * Age ≥ 18 years * Symptoms based on the following criteria: Persistent or intermittent nonpainful sensation of a lump or foreign body in the throat with no structural lesion identified on physical examination, laryngoscopy, or endoscopy. 1. Occurrence of the sensation between meals. 2. Absence of dysphagia or odynophagia Exclusion Criteria: * Subjects with psychological disease * Significant heart disease and/or arrhythmia * Proton Pump inhibitors and/or Histamine 2 Receptor Antagonist use within 2 weeks before randomization * Mono-amine Oxidase inhibitors or Selective Serotonin Reuptake Inhibitor or Tricyclic antidepressant use within 2 weeks before randomization * History of drug allergy that use in research * Pregnancy or breast feeding * Decline to participate in study