Myasthenia Gravis and Psyche

N/ACompletedNCT03205306

Charite University, Berlin, Germany1,399 enrolled

Overview

The purpose of the study is to systematically capture and characterize mental comorbidities for patients with myasthenia gravis. Anxiety disorders and depression for example, can negatively affect the quality of life and lead to e.g. unemployment and early retirement especially in young patients. Additionally the researchers want to find out in what way certain aspects of the disease have an influence on the quality of life, and whether different concepts of coping with the disease have different effects on the quality of life for patients with myasthenia gravis. During the study, close relatives of patients will also be asked to provide input about their current stress situation in the context of supporting their relative. Based on the results, the investigators want to improve and supplement established treatment concepts, to ensure a more comprehensive and individual treatment.

Study Type

OBSERVATIONAL

Enrollment

1,399

Conditions

Myasthenia Gravis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with Myasthenia Gravis * Age ≥18 years Exclusion Criteria: * N/A

Locations (1)

NeuroCure Clinical Research Center (NCRC), Charité

Berlin, Germany

Outcomes

Primary Outcomes

Questionnaire Survey (Patient)

* Questionnaire for self-completion by patients containing questions about general information, information on myasthenia, information on diagnosis of mental illness and psychotherapeutic care * Hospital Anxiety and Depression Scale (HADS - questionnaire for self-completion by patients to determine the levels of anxiety and depression) * Breslau scale PTBS-7 (questionnaire for self-completion by patients to determine the levels of Probability of posttraumatic stress disorder (PTSD)) * Mya Quality of Life 15 (Mya QoL15 - questionnaire for self-completion by patients for use as a measure of health outcome) * Freiburg questionnaire for coping (FKV - questionnaire is used to assess disease processing modes at the levels of cognition, emotion, and behavior)

Time frame: directly after inclusion in the study

Secondary Outcomes

"Häusliche Pflegeskala" (HPS)

questionnaire is used to assess social work Intervention and couple's counselling

Time frame: directly after inclusion in the study