Serum Lipids and Glucose Levels in Relation to CVD Outcomes in Patients With Ischemic Heart Failure

N/AUnknownNCT03206593

Guangdong Provincial People's Hospital2,000 enrolled

Overview

Current prospective cohort study is to evaluate the association between fasting lipid profiles (including total cholesterol, low density lipoprotein-cholesterol, high density lipoprotein-cholesterol, triglycerides, apolipoprotein A, apolipoprotein B and lipoprotein(a)) and fasting plasma glucose at admission with cardiovascular disease outcomes (including fatal and non-fatal myocardial infarction, fatal and non-fatal ischemic stroke, re-hospitalization due to heart failure, revascularization by percutaneous coronary intervention or coronary artery bypass grafting, or cardiovascular mortality) and all-cause mortality.in patients with ischemic heart failure and left ventricular ejection fraction \< 45 % evaluated by echocardiography during 12 months follow-up.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Ischemic Heart Failure Lipids Fasting Plasma Glucose Cardiovascular Outcomes All-cause Mortality

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1.Diagnosed as coronary artery disease by coronary angiography; 2. Left ventricular ejection fraction \< 45% evaluated by echocardiography during index hospitalization. \- Exclusion Criteria: Coexistent malignant diseases; stage 3 or more of chronic kidney disease; liver dysfunction with ALT or AST higher than 3 times of normal limit range; do not want to participant in current study \-

Outcomes

Primary Outcomes

Cardiovascular diseases outcomes

Fatal or non-fatal myocardial infarction, fatal or non-fatal ischemic stroke, re-hospitalization due to heart failure, revascularization by percutaneous coronary intervention or coronary artery bypass grafting, and cardiovascular mortality

Time frame: 12 months after discharge from index hospitalization

Secondary Outcomes

All-cause mortality