Expanded Access to Provide Selitrectinib for the Treatment of Cancers With a NTRK Gene Fusion

N/ANo Longer AvailableNCT03206931

Bayer

Overview

Selitrectinib expanded access is for minor and adult patients with cancer having a change in a particular gene (NTRK1, NTRK2, or NTRK3 gene fusion). The patients are ineligible for an ongoing selitrectinib clinical trial or have other considerations that prevent access to selitrectinib through an existing clinical trial. Expanded access is intended to treat individual patients with different types of cancers with a NTRK gene fusion, including blood cancers, who have previously received tropomyosin receptor kinase (TRK) inhibitor therapy.

Study Type

EXPANDED_ACCESS

Conditions

Solid Tumors Harboring NTRK Fusion

Interventions

Selitrectinib (BAY2731954)DRUG

Selitrectinib is administered as capsules or liquid formulation.

Eligibility

Sex: ALLMin age: 1 Month

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of cancer with a NTRK1, NTRK2, and NTRK3 gene fusion * Previous treatment with a kinase inhibitor with known activity on TRK inhibition * Unable to participate in an ongoing selitrectinib clinical trial * Medically suitable for treatment with selitrectinib Exclusion Criteria: * Currently enrolled in an ongoing clinical study with a TRK inhibitor

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.