Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Key Inclusion Criteria: 1. Diagnostic report had to include evidence for morphological and cyclin D1 or t (11; 14). 2. Eastern Cooperative Oncology Group performance status of 0-2. 3. Measurable disease by computed tomography/magnetic resonance imaging. 4. Received prior regimens for MCL. 5. Documented failure to achieve any response, (stable disease or progressive disease during treatment) or documented progressive disease after response to the most recent treatment regimen. 6. Aspartate aminotransferase and alanine aminotransferase ≤ 2.5 x upper limit of normal (ULN). 7. Total bilirubin ≤ 2 x ULN (unless documented Gilbert's syndrome). 8. Life expectancy of \> 4 months. Key Exclusion Criteria: 1. Current or history of central nervous system lymphoma. 2. Prior exposure to a BTK inhibitor before enrollment. 3. Prior corticosteroids with anti-neoplastic intent within 7 days. 4. Major surgery within 4 weeks of screening. 5. Toxicity must have recovered from prior chemotherapy. 6. History of other active malignancies within 2 years of study entry. 7. Currently clinically significant active cardiovascular disease. 8. QT interval corrected with Fridericia's formula \> 450 microseconds or other significant electrocardiogram abnormalities. 9. Uncontrolled systemic infection or infection requiring parenteral anti-microbial therapy. 10. Known human immunodeficiency virus infection, or active hepatitis B or hepatitis C infection (detected positive by polymerase chain reaction). Note: Other protocol-defined Inclusion/Exclusion criteria may apply.