An Interventional Multidisciplinary Approach to Individualize Blood Pressure Treatment

N/AActive Not RecruitingNCT03209154

Oslo University Hospital1,000 enrolled

Overview

The aim of the study is to investigate and explore the most important aspects of drug-adherence in the treatment of hypertension in order to improve treatment and blood pressure control, implying that new knowledge will reduce morbidity and mortality.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

1,000

Conditions

Uncontrolled Hypertension

Interventions

Therapeutic drug monitoringDIAGNOSTIC_TEST

Therapeutic drug monitoring will be performed.

Home blood pressure monitoringDEVICE

Patients will perform home blood pressure monitoring at home.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Signed informed consent * Uncontrolled hypertension * A stable medication regimen for at least 4 weeks of ≥ 2 antihypertensive agents * No planned changes in antihypertensive drugs Exclusion Criteria: * Withdrawal of consent * 24-h systolic ambulatory blood pressure \>/= 170 mmHg * Patients with inadequate Norwegian language skills * Positive pregnancy test * Known alcohol or drug abuse * estimated glomerular filtration rate \<30 mL/min/1.73m2 * Albumin/creatinin ratio \>300 mg/mmol * Any reason why, in the opinion of the investigator, the patient should not participate

Locations (1)

Oslo University Hospital

Oslo, Norway

Outcomes

Primary Outcomes

Blood pressure control

Change in systolic daytime ambulatory blood pressure.

Time frame: 3 months after baseline

Data from ClinicalTrials.gov

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