Interventional, comparative, open-label, single-center study to demonstrate that early (from 6 months of age) and systematic (every 6 months) screening for Obstructive Sleep Apnoea (OSA) by polysomnography (PSG) in infants with Down syndrome during the first 3 years of life is associated with improved neurodevelopment at 3 years of age, with sustained benefits up to 5 years of age.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
80
PSG will be perfomed every 6 months in the Study group from the age of 6 months to 3 years
Institut Jérome Lejeune
Paris, Sélectionnez l'État/Province, France
Median Griffiths Scales of Child Development, Third Edition (Griffiths III) Scores
Median Griffiths III scores at the age of 3 years will be compared between the 2 groups
Time frame: At the age of 3 years
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