We aim to evaluate the change in optic nerve sheath diameters as a surrogate of intracranial pressure before and after mannitol administration in patients who undergo robot assisted laparoscopic radical prostatectomy with pneumoperitoneum and Trendelenburg position.
Mannitol has been frequently used for renal protection during surgery. Optic nerve sheath diameter is used to evaluate intracranial pressure noninvasively. Robot-assisted laparoscopic radical prostatectomy can induce an increase in optic nerve sheath diameter due to Trendelenburg position and carbon dioxide insufflation. We therefore aim to evaluate the change in optic nerve sheath diameters before and after mannitol administration in patients who undergo robot assisted laparoscopic radical prostatectomy.
Study Type
OBSERVATIONAL
Enrollment
39
The mannitol has been administered routinely to prevent renal dysfunction in patients undergoing robot-assisted laparoscopic radical prostatectomy. Participants will receive the mannitol as part of routine medical care, and we will evaluate the change in optic nerve sheath diameters before and after mannitol administration.
Asan Medical center
Seoul, South Korea
Change in optic nerve sheath diameters
Change in optic nerve sheath diameters before and after mannitol administration
Time frame: 5 minutes after pneumoperitoneum and Trendelenburg position, 90 minutes after mannitol administration during pneumoperitoneum and Trendelenburg position
Change in optic nerve sheath diameters
Change in optic nerve sheath diameters before and after mannitol administration
Time frame: 5 minutes after pneumoperitoneum and Trendelenburg position, 60 minutes after mannitol administration during pneumoperitoneum and Trendelenburg position
Change in optic nerve sheath diameters
Change in optic nerve sheath diameters before and after mannitol administration
Time frame: 5 minutes after pneumoperitoneum and Trendelenburg position, 30 minutes after mannitol administration during pneumoperitoneum and Trendelenburg position
Optic nerve sheath diameter
Optic nerve sheath diameter before mannitol administration
Time frame: 10 minutes after induction of anesthesia
Optic nerve sheath diameter
Optic nerve sheath diameter after mannitol administration
Time frame: Intraoperative (during skin closure)
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