Certain Maternal Antibodies in Relation to Doppler in Hypertension With Pregnancy

Cairo University100 enrolled

Overview

Relation of certain maternal serum antibodies to Doppler changes will be studied in cases suffering from hypertension with pregnancy.

Assessment will be done for maternal serum anti-beta 2 glycoprotein 1 antibodies and anticardiolipin antibodies in cases of preeclampsia after 32 weeks of pregnancy. In addition, fetal Doppler changes will be assessed.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Pre-Eclampsia

Interventions

DopplerDIAGNOSTIC_TEST

Doppler will be done to pregnant women with Pre-Eclampsia

serum antibodiesDIAGNOSTIC_TEST

serum antibodies will be measured for pregnant women with Pre-Eclampsia

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant women 32 weeks or more gestational age * Pre-eclampsia * Singleton pregnancy Exclusion Criteria: * Intrauterine fetal death * Fetus with apparent congenital anomalies * Pregnant females with other medical disorders * History of essential hypertension. * History of antepartum hemorrhage. * History of rupture of membranes.

Locations (1)

Department of Obstetrics and Gynecology

Cairo, Greater Cairo, Egypt

Outcomes

Primary Outcomes

percentage of cases that develop severe pre-eclampsia

percentage of cases that develop severe pre-eclampsia will be assessed by an investigator

Time frame: It will be calculated after 1 year from the start of the study

Central Contacts

Doaa Sh Belal, MD

CONTACT

0020223682030 doaash@live.com

Data from ClinicalTrials.gov

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