A randomized controlled trial (RCT) in patients who underwent sphincter preserving surgery due to rectal cancer. The study will analyze the effect of Transanal irrigation (TAI) and medication that can help control of the bowel movement in patients with low anterior resection syndrome.
A randomized controlled trial (RCT) in patients who underwent sphincter preserving surgery due to rectal cancer. The study will analyze the effect of Transanal irrigation (TAI) and medication that can help control of the bowel movement in patients with low anterior resection syndrome. An interim analysis will be made after 40 included patients in the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
45
Effect of Transanal irrigation (TAI) using Peristeen® anal irrigation system - Coloplast
Medication to help control of the bowel movement (One or a combination of Loperamide, Sorbitol, Sterculia gum)
Danderyd Hospital
Stockholm, Sweden
Karolinska University Hospital
Stockholm, Sweden
Stockholm South General Hospital
Stockholm, Sweden
Bowel function
Cleveland incontinence questionnaire
Time frame: 1 year
Bowel function, Low anterior resection syndrome (LARS)
Assessed using LARS questionnaire (score 0-42, a high score indicates poor bowel function)
Time frame: 1 year
Quality of Life (QoL)
Assessed using EORTC Quality of life questionnaire (QLQ)-C30
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.