Home Respiratory Rehabilitation in Advanced Lung Cancer Chemotherapy Per os

Inclusion Criteria: * Patient with advanced or metastatic lung cancer * In the course of treatment by oral chemotherapy of oral targeted therapy (tyrosine kinase inhibitor) in 1st, 2nd, 3rd line or more at the time of their inclusion * Diagnosis of CP retained after multidisciplinary discussion of patient records Exclusion Criteria: * Any residual toxicity of a previous antineoplastic treatment, grade\> 2. * Cardio-respiratory contraindications to exercise re-training: * Angina unstable * Recent infarct * Tight aortic stenosis * Unsteady heart failure * Pericarditis, endocarditis, myocarditis * Evolutionary thromboembolic disease * Ventricular aneurysm * Intra ventricular thrombus * Uncontrolled rhythm disorders * Instability of the respiratory state defined by uncompensated respiratory acidosis * Carcinological contraindications: * Bone metastases at risk of fracture and / or algae despite optimal analgesic treatment, symptomatic central nervous system metastases * Presence of anemia (Hb \<8g / dl or \<10g / dl if patient with previous cardiac history), thrombocytopenia (\<100,000 platelets / mm3) * Chimio toxicity (neurological, cardiac) according to the investigator's assessment * Neuromuscular contraindications: * Neuromuscular and / or osteo-articular disease making it impossible to re-train * Severe cognitive impairment * Patient under tutorship or curatorship