The Jiaxing Birth Cohort in China

Zhejiang University500,000 enrolled

Overview

The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.

Study Type

OBSERVATIONAL

Enrollment

500,000

Conditions

Childhood Obesity Anemia Pregnancy Complications Pregnancy; Hypertension Feeding Behavior

Interventions

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Pregnant women came to clinic visit at one of the local hospitals during pregnancy at Jiaxing area 2. Pregnant women were followed up during pregnancy and their children were born alive at local hospital or clinics Exclusion Criteria: 1. Those who did not want to participant 2. The infant was dead at the birth 3. Those pregnant mothers who dropped out during follow-up at pregnancy or moved out of the Jiaxing area

Outcomes

Primary Outcomes

overweight and obesity

BMI-z-score was calculated from height and weight. BMI-z-score\>1 was defined as overweight/obesity

Time frame: Up to 6-7 years old for these children

Central Contacts

Duo Li, PhD

CONTACT

duoli@zju.edu.cn

Ju-Sheng Zheng, PhD